Tuesday, September 15, 2020

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Friday, September 11, 2020

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Thursday, September 10, 2020

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Monday, September 7, 2020

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Wednesday, September 2, 2020

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Friday, August 28, 2020

Term Papers That Surpass Your Teachers Expectations!

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Wednesday, August 26, 2020

Best Help With Writing A Term Paper

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Sunday, June 7, 2020

One for All and All for None Grammatical Rules for One, Neither, and Each!

In this blog post, our resident grammar girl reviews the impossibly confusing rules for singular subjects that refer to plural groups; subject-verb agreements involving"each", "all", and "none"; and last (but not least!) "neither", "neither", and "nor" and how they relate to your verb choice. 1. One is the loneliest number, but it's not always single One of the grammatical concepts that confuse people most is the construction of sentences like this one. What makes it confusing? The singular subject that refers to part of a plural group. One is singular while grammatical concepts are plural. The verb in question is confuse – should it be confuse (plural) or confuses (singular)? In fact, there are multiple accepted explanations for what constitutes the correct usage. Generally, the plural is what sources use most. The New York Times After Deadline blog explored this theme in a post from 2009 called One of Those Things, in which the author demonstrates why the plural verb makes sense: In our example above, confuse is the verb that agrees with grammatical concepts, qualified by the pronoun that to form this relative clause. Grammatical concepts confuse people. The alternative – grammatical concepts confuses people – looks and sounds immediately incorrect. The difficulty arises because one grammatical concept confuses, so the singular form of the verb does not necessarily appear to be wrong when it is linked to the initial subject of one. When put together with the rest of the sentence, however, it makes more sense to use the plural, according to the New York Times Style Guide. Re-ordering the words more clearly reveals this logic: Of the grammatical concepts that confuse people, one is the construction of sentences like this one. 2.Each of us wants to know the rule Another related concept that poses challenges to subject-verb agreement involves the subjects "each", "all", and "none". Each Which sentence is correct? Each of the kids wants a Popsicle. Each of the kids want a Popsicle. The first sentence is correct. To make this more apparent, substitute each one and it becomes Each one of the kids wants a Popsicle because one kid wants. Each always refers to one out of a group. In cases in which each is not the subject, there may be a plural subject before it and therefore a plural verb that follows, such as in: They each want their own dessert. (The alternative would be They each wants their own dessert, which is clearly wrong). None None is a little more nuanced. Unlike each, which is always singular, none can be singular or plural depending on the context, according to the Oxford English Dictionary and others. When none stands in as a shortened form of no one, as was its original purpose, it can be followed by a singular verb. For example: None of us is tall. (Not one of us is tall.) When none means not any, the subsequent verb is plural: None of the students are absent. (Not any of the students are absent from school.) None of the jewels were stolen. (Not any of the jewels were stolen). The distinction is subtle, and in these instances, it would also be correct to use the singular verb. Grammarians have identified a rule of thumb to follow in order to determine when none calls for a singular or plural verb. When the implied noun to which none applies represents a singular thing, use the singular verb: None (of the snow) was melting. When the implied noun to which none refers represents a plural thing, use the plural verb: None (of the plates) were clean. All The indefinite pronoun all may also be singular or plural depending on the thing to which it refers. All of the pieces complete the puzzle. The pieces are plural, and all of them together complete the puzzle. At the same time, all of the cake was eaten. The cake is singular, and all of it was eaten. When referring to people, this should appear clearer: all of the people were dancing. Since the word people is always plural, all of the people accordingly is always plural. The same goes for a plural pronoun: all of us were dancing. 3. You say either, I say neither In constructions that use the words either and neither (however you choose to pronounce them), the context determines whether to use a single or plural verb. Grammatically, either and neither are considered singular. Either works When there is a choice between two items, use the word either with a singular verb to follow: Either of the restaurants is a good choice. It might be easier to think of this as either one of the restaurants, where one is singular, and either one is a good choice. Consider the alternative: either of the restaurants are a good choice. Although restaurants is plural, this sentence as a whole should sound incorrect because either is, NOT either are. Some other examples of the correct use of either include: Does either of you know a good restaurant? (NOT: Do either of you know) Let's get some ice cream, if either of you wants it. (NOT: If either of you want) Neither is the same With neither, the subsequent verb is also singular when identifying a choice of two items. Neither restaurant was very good. Again, consider that neither one of the restaurants was very good. The alternative should also sound incorrect: neither restaurant were very good. Some more examples include: Neither of us wants to play tennis today. (NOT: Neither of us want) Neither of these shops has the jacket in my size. (NOT: Neither of these shops have) Either/Or The singular rule holds true in either/or scenarios when both items being compared are singular: Either the blue shirt or the green shirt was my favorite. My favorite was either the blue shirt or the green shirt. Either my sister or my brother is going to make breakfast. My sister is going to make breakfast, or my brother is going to make breakfast. Either/or applies to positive comparisons, whereas neither/nor applies to negative comparisons. Neither/Nor Like the positive counterparts, neither/nor scenarios also contain singular verbs when comparing two singular items: Neither the bracelet nor the necklace was silver. Neither my brother nor my sister knows how to cook. According to some, a rule of proximity suggests that a plural noun may follow in phrases with either and neither if the noun closest to the verb is plural. For example: Either the coach or the players receive the trophy. (The coach receives the trophy, but the players receive the trophy. Because the plural noun players is the closest to the verb, the verb agrees accordingly with the plural noun.) Neither my brother nor my sisters have pets. (My brother has no pets but my sisters have no pets. Since my sisters is within closer proximity to the verb, the verb agrees with the plural subject my sisters). A comprehensive list of examples that demonstrate the correct use of either and neither can be found here. Are you interested in New York or Cambridge tutoring for your grammar and English work? ; Read more from our resident grammar expert below: The Most Common Prefixes and Their Meanings Possessive Plurals and Plurals' Possessives Semi-colons, Colons, and Commas: How and When To Use Them

Sunday, May 17, 2020

Can You Eat Mango Skin Urushiol and Contact Dermatitis

Eating the skin of a mango depends on a few different factors. Heres a look at the good ​chemicals in mango, as well as one that can cause a nasty reaction. Mango Skin Nutrients and Toxins Although the pit of a mango isnt considered edible, some people do eat the mango skin. The skin is bitter-tasting, but the peel contains several healthful chemical compounds, including powerful antioxidants mangiferin, norathyriol, and resveratrol. However, mango skin also contains urushiol, the irritating compound found in poison ivy and poison oak. If you are sensitive to the compound, eating mango skin can cause a nasty reaction and may send you to the doctor. Contact dermatitis is more common from handling mango vines or peeling the fruit. Some people suffer reactions from eating mango, even if they are peeled. If you have a strong reaction to poison ivy, poison oak, or poison sumac, you may wish to avoid the risk associated with eating mango skin. In addition to mango, pistachio nuts are another food that may cause contact dermatitis from urushiol. Symptoms of the Reaction to Mango Skin Contact dermatitis from urushiol, whether comes from mango skin or another source, is a Type IV hypersensitivity reaction. This type of reaction is delayed, meaning the symptoms dont show up immediately. For the first reaction, it may take 10 to 21 days for symptoms to appear, by which time it may be hard to identify the source of the reaction. Once an urushiol allergy develops, exposure leads to a rash within 48 to 72 hours of exposure. The rash is characterized by redness and swelling, sometimes with streaking, papules, blisters, or vesicles. It may appear on and around the mouth and extend to the throat and eyes. In minor cases, the rash resolves on its own in a week or two. However, the rash may persist as long as five weeks. Scratching the rash can result in an infection, typically from Staphylococcus or Streptococcus. The infection may require antibiotics. In the case of a severe allergic reaction, a systemic allergic response may occur. Soap and water can be used to remove traces of urushiol from skin, but most people dont know they have a problem until the rash appears. The allergic response may be treated with oral antihistamines (e.g., Benadryl), topical antihistamines, or the steroids prednisone or triamcinolone in extreme cases. References Shenefelt, Philip D. (2011). Herbal Treatment for Dermatologic Disorders. Herbal Medicine: Biomolecular and Clinical Aspects (2nd ed.). Boca Raton, Florida, USA: CRC Press.Stibich, A. S.; Yagan, M.; Sharma, V.; Herndon, B. Montgomery, C. (2001). Cost-effective post-exposure prevention of poison ivy dermatitis.  International Journal of Dermatology.  Ã¢â‚¬â€¹39  (7): 515–518.

Wednesday, May 6, 2020

Autism Disorder Essay - 1832 Words

Autism is a pervasive developmental disorder of the brain that severely impacts socialization, communication, and may even cause obsessive or repetitive behaviors. Autism delays the brains normal development, and is also correlated with a milder form of the syndrome known as a pervasive developmental disorder not otherwise specified (PDD-N OS). Since it was first identified in 1943, there has been increasing rate in new diagnoses each year. Muhle, Trenracoste, and Rapin (2004) found that the rate of diagnosis for Autism has risen 556% between the years of 1991 and 1997. Many feel that this increase is due to a shifting of diagnostic criteria, or newer defining characteristics of the syndrome. The expansion of the diagnostic criteria†¦show more content†¦Because men lack the extra or â€Å"back-up† X chromosome that women have, they are more likely to develop symptoms of Autism, while women have the extra X chromosome to function with if there are abnormalities on th eir first. Along with the high prevalence of Autism in boys, there also seems to be a high ratio of twins that also develop the disorder. Muhle et al., (2004) found through studies, that nearly 60% of monozygotic twins, or identical twins, showed similarities in that both twins shared classic Autistic traits. On the other hand, in dizygotic twins, or fraternal twins, they found 0% similarities in sharing classic Autistic traits. Findings like these suggest that an underlying cause of Autism may be found in genes. Autism was first brought to the world’s attention by a child psychiatrist named Leo Kanner. He published his first article, bringing the world up to date on a new disorder called Autism in 1943. His article was called â€Å"Autistic Disturbances of Affective Contact†, and talked about his case studies. Kanner said that he had seen instances of these types of children as early as 1938. In his article he discusses his case studies of eleven children, of which ei ght were boys and 3 girls. Early on you can see that there was still a higher prevalence of boys diagnosed with Autism. On the other side of the spectrum, was a man named Bruno Bettelheim, who also studied the Autism disorder. Bettelheim, in large part, came up with the theory of the refrigeratorShow MoreRelatedAutism Spectrum Disorder ( Autism )900 Words   |  4 Pages Autism Disorder Mohamed Ayoub Community College of Aurora Autism Spectrum Disorder We are living in a time where a remarkable and advanced medical treatments exist. However, scientists and medical professionals are constantly faced with diseases and disorders that contemporary humanity needs a cure and treatment. Amongst the disorders that affecting our young people today is the autism spectrum disorder. It is a â€Å"complex and life long behavioral disorder marked by impairment in socialRead MoreAutism Spectrum Disorder ( Autism ) Essay1396 Words   |  6 PagesThe disorders listed under the umbrella of Autism Spectrum Disorder, were once listed as autism and subtypes of autism. This was changed in 2013 when The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) was published, and they were listed under the umbrella of Autism Spectrum Disorder. There are five disorders listed under the umbrella of Autism Spectrum Disorder: Autistic Disorder, Asperger’s Syndrome, Childhood Disintegrative Disorder, Rett Syndrome and Pervasive Dev elopmentalRead MoreThe Autism Spectrum Disorder ( Autism )1025 Words   |  5 PagesI. Introduction: Autism Spectrum Disorder is a range of complex neurodevelopment disorders, characterized by social impairments, communication difficulties, and restricted, repetitive, and stereotyped patterns of behavior. There is more classification of Autism that is based on the severity of symptom. Childhood disintegrative disorder, also known as Heller s syndrome is a rare condition characterized by a late onset of developmental delays in language, social function, and motor skills. AspergerRead MoreAutism Spectrum Disorder And Autism1590 Words   |  7 PagesAutism Spectrum Disorder, more commonly known as Autism, is a prevalent developmental disorder that has grown to a major extent recently in the United States, UK, Japan and Europe as well (Landrigan 219). According to an article written in 2014 by Chris Bateman, 1 in every 50 children aged 6-17 in the United States are diagnosed with autism, compared to decades ago where it wasn’t nearly anywhere close to that (Bateman 1). As autis m continues to grow, it is important that we learn about the differentRead MoreAutism Spectrum Disorder And Autism1389 Words   |  6 Pages Autism Spectrum Disorder Autism is a form of â€Å"ASD,† Autism Spectrum disorder and is experienced all around the world. Autism is a developmental disorder that consists of many neurodevelopmental disorders of the brain. People with autistic disorder think and act in different ways than most people. There are many different forms of autism spectrum disorder that include the pervasive development disorder, Asperger syndrome, and autistic disorder. These disorders are called spectrum disorders becauseRead MoreAutism Spectrum Disorder And Autism1492 Words   |  6 Pageslife there are several different disorders that have been well known from many years ago. There is one disorder that was diagnosed in the early 1800’s but it wasn’t until a few years ago that it gained lots of attention. What used to be known as Autism was later renamed in the DSM to Autism Spectrum Disorder meaning, a neurodevelopmental disorder rather than a pervasive developmental disorder (Gargiulo, 2015). Autism s pectrum disorder is a developmental disorder characterized by abnormal or impairedRead MoreAutism And Autism Spectrum Disorder Essay1500 Words   |  6 PagesSzopinski English III 29 April 2016 Autism Scientifically, autism and autism spectrum disorder, also known as ASD, are commonly used names for difficult disorders that have to do with brain development. Disorders like these are grouped by someone’s difficulty in social interaction, repetitive behaviors, and nonverbal communication. To the people who are diagnosed with this disorder and the families it affects; it is so much more than just science. Autism had many different names and age whenRead MoreAutism Spectrum Disorder And Autism Essay1474 Words   |  6 Pagesof the most widely known abnormal disorders is Autism Spectrum Disorder. Autism is a complicated disorder because it represents a wide range of developmental disorders categorized by criteria such as: impaired social interactions, verbal and nonverbal communication breakdowns, and repetitive behaviors. Since Autism Spectrum Disorder is on a spectrum, as the name suggests, there are individuals with mild to little symptoms classified by Autism Spectrum Disorder and others who classify severely inRead MoreThe Autism Spectrum Disorder ( Autism )1826 Words   |  8 PagesAutism is also known as classical autism as well as an autism spectrum disorder or ASD. Classical autism is one of the five types of autism spectrum disorders in which all are developmental brain disorders. The development disability challenges children to have social, communication and language problems and a limited range of activities and interests. The other types of autism spectrum disorder include Asperger syndrome, childhood disintegrative disorder, Rett syndrome, and pervasive developmentalRead MoreAutism Spectrum Disorder And Autism Essay2310 Words   |  10 Pagesperson who has Autism? Growing up with a person with Autism can be a challenge for the whole family. However, a person with Autism teaches the peo ple around them how to adjust to situations in different manners as opposed to the traditional ways that are inculcated. This report will consist of both my personal experience with my younger brother who lives with Autism as well as important details about Autism Spectrum Disorder. According to the National Institute of Neurological Disorders and Stroke

Financial Instability Essay Example For Students

Financial Instability Essay The soaring volume of international finance and increasedinterdependence in recent decades has increased concerns about volatility andthreats of a financial crisis. This has led many to investigate and analyze theorigins, transmission, effects and policies aimed to impede financialinstability. This paper argues that financial liberalization and speculationare the most reflective explanations for instability in financial markets andthat financial instability is likely to be transmitted globally with farreaching implications on real sector performance. I conclude the paper with theargument that a global transaction tax would be the most effective policy tocurb financial instability and that other proposed policies, such as targetzones and the creation of a supranational institution, are either unfeasible orunattainable. INSTABILITY IN FINANCIAL MARKETSIn this section I examine four interpretations of how financialinstability arises. The first interpretation deals with speculation and thesubsequent bandwagoning in financial markets. The second is a politicalinterpretation dealing with the declining status of a hegemonic anchor of thefinancial system.The question of whether regulation causes or mitigatesfinancial instability is raised by the third interpretation; while the fourthview deals with the trigger point phenomena. To fully comprehend these interpretations we must first understand anddifferentiate between a currency and contagion crisis. A currency crisisrefers to a situation is which a loss of confidence in a countrys currencyprovokes capital flight. Conversely, a contagion crisis refers to a loss ofconfidence in the assets denominated in a particular currency and the subsequentglobal transmission of this shock. One of the more paramount readings of financial instability pertains tospeculation. Speculation is exhibited in a situation where a governmentmonetary or fiscal policy (or action) leads investors to believe that thecurrency of that particular nation will either appreciate or depreciate in termsrelative to those of other countries. Closely associated with these speculativeattacks is what is coined the bandwagon effect.Say for example, that acountrys central bank decides to undertake an expansionary monetary policy.Aneoclassical interpretation tells us that this will lower the domestic interestrates, thus lowering the rate of return in the foreign exchange market andbringing about a currency depreciation. As investors foresee this happeningthey will likely pull out before the perceived depreciation. Efforts to getout would accelerate the loss of reserves, provoking an earlier collapse,speculators would therefore try to get out still earlier, and so on (Krugman,1991:93). This herding or bandwagon effect naturally cause wild swings inexchange rates and volatility in markets. Another argument for the evolution of financial market instability isclosely related to hegemonic stability theory. This political explanationpredicts a circumstance (i.e. a decline of a hegemons status) in which a lossof confidence in a particular countries currency may lead to capital flightaway from that currency. This flight in turn not only depreciates the currencyof the former hegemon but more importantly undermines its role as theinternational financial anchor and is said to ultimately lead to instability. The trigger point phenomena may also be used as an instrument to explainfinancial instability. Similar to the speculative cycles described above, thisrefers to a situation where a group of investors commits to buy or sell acurrency when that currency reaches a certain price level. If that particularcurrency were to rise or fall to that specified level, whether by real orspeculative reasons, the precommited investors buy or sell that currency orassets. This results in a cascade effect that, like speculative cycles,increases or decreases the value of the currency to remarkably higher or lowerlevels. Country after country has deregulated its financial markets andinstitutions. The neoclassical interpretation asserts that regulation is thoughtto create incentives for risk taking and hence instability. It is said to bringabout what are called moral hazards. Proponents of deregulation argue thatwhen people are insured, they are more apt to take greater risks with theirinvestments in financial markets. The riskier the investment activity, the morevolatile the markets tend to be. A closer look suggests that perhaps only two of these explanations arevalid when thinking about the origins of financial instability. The triggerpoint explanation seems to be a misreading of the origins of instability. It isunlikely that a large number of investors would have the incentive oroperational ability in order to simultaneously coordinate the buying or sellingof a currency or assets denominated in that currency. If even there is suchunlikely coordination, the existence of even a very large group of investorswith trigger points need not create a crisis if other investors know they arethere (Krugman, 1991:96). The theory of hegemonic stability also overlooks a number of factorsthat can provide useful insights in explaining the emergence of financialinstability. Historical precedence supports this assertion. For instance,Britains role as international economic manager was very minor in the stabilityexperienced under the gold standard. The success of the standard can beattributed to endogenous factors such as the self adjusting market mechanism andthe informal discipline maintained by its rules. The destabilization of thegold standard can be attributed to the extreme domestic economic and financialpressures brought on nation states by World War I, and not solely on theindustrial and economic demise of Britain. A valid explanation for the origins of financial instability are thespeculative attacks brought on by investors. Although similar in function totrigger points, these speculative cycles cannot be mitigated simply by purerecognition. Rather than acting on the value of the currency itself,speculators act on occurrences or policies that will alter the value of thecurrency. Instability arises from the fact that these speculative cycles inducecapital flight and therefore a change in the value of that particular currency,whether or not the decisions of these investors are based on market fundamentals. Futures, options, swaps and other financial instruments havegiven investors and speculators an unheard of capacity to leverage financialmarkets. The greater the leverage, the greater the instability (McCallum,1995:12). If we examine the deregulatory process closely, it becomes clear thatthere is a perverse relationship between deregulation and financial stability. Say for example, investors suffer from a profit squeeze. This causes theinvestors to lobby politicians for deregulation. The resulting wave ofderegulation fosters instability and wide swings in exchange rates which in turncause loan defaults and subsequent banking crisis. The resulting financialinstability thus begs calls regulation, likely placing the investors in theoriginal position with an unsolved problem. We can see that the dialectic ofthe regulatory process undermines anticipated stability and will eventually leadto financial instability and collapse. In this environment, there arises callsfor new forms of financial regulation. These policies and proposals are ofcritical importance and will therefore be discussed later in the paper. THE TRANSMISSION AND EFFECTS OF FINANCIAL INSTABILITYThere are three contending albeit interrelated views on how financialinstability may be transmitted globally. These include equity markets,multiplier effects and monetary reverberations. Aaron Burr Treason Trial EssayThe last major policy aimed at quelling financial instability is thecreation of a supranational institution aimed at coordinating financial reformand adopting a system of regulatory supervision. Processing along the lines ofa Bretton Woods architecture, this would in a sense institutionalize the role ofa hegemon with a creation of a common currency for all of the industrialdemocracies and a joint Bank of Issue to determine monetary and financialpolicies (Cooper, 1984:166). This policy proposal endorses the adoption of anglobal financial institution managing the operation of coordinated supervision. Experience shows us that coordinated supervision is not possible ininternational financial markets. For instance, the Basel Concordant was neverable to reach organizational level to properly respond to a crisis. Additionally, the BCCI affair demonstrated the limitations of internationalbank supervision when confronted by unscrupulous operators intent on exploitingthe gaps in national bank supervisory systems (Herring and Litan, 1995:105). Proponents of re-creating a Bretton Woods-type system are unaware of thelessons to be learned from that period. The theoretical brethren of hegemonicstability advocates, proponents of this policy seek too place the direction ofworld monetary policy in the hands of a single country or institution thatwould have great influence over the economic destiny of others (Williamson,1977:37). As seen under the Bretton Woods system the destiny of others was inthe hands of a country that was unable to maintain stability. It is yet to bedemonstrated how an institutional framework would sidestep the same faultlinesand management problems experienced by the United States under the Bretton Woodsregime. The organizational barriers to creating such cooperation andcoordination would be insurmountable. Secondly, whose view would most likely bepresented in the supranational forum? Experience in international organizationsshows us that it will probably be the powerful, industrialized nations. Thevoice and needs of the less developed countries is likely to be marginalized andsituations such as the Latin American debt crisis would continue to occur. When looking at the progress of the European Monetary Union we see thatthe completion of a single market is far too radical for todays internationalfinancial climate. Just as the costs of qualifying for the EMU has become toohigh it becomes unrealistic to hope that the major industrial countries canmake comparable strides toward political much less financial unification inour lifetime (Eichengreen and Tobin, 1995:170). Ideally, the best policy for stemming financial instability andspillover effects would be one that extinguishes the problem at its roots. Ifderegulation in itself causes instability in financial markets, then regulationwould be appealing. Even when the benefits of financial deregulation areapparent, there is a role for regulatory policy that would leave the worldeconomy less vulnerable to financial collapse (Eichengreen and Portes, 1987:51). . If we also hold true the conclusion that the best explanation for financialinstability is speculation, then a global securities transaction tax such as theone proposed by Tobin would be optimal. The discouragement of short termspeculative excursions and the endorsement of long-term investment willeliminate the problem of volatility based on speculative attacks that so oftenstray from market fundamentals.Critics are quite correct when they arguethat the tax could induce financial arbitrage and substitution. However thisproblem would be solved as long as the tax was globally adopted. Secondly, thetax would be applied to goods, services, and financial instruments that had fewor no substitutes. The view that the creation of new government revenues isoverestimated and that Third World countries would carry the financial burden isnullified when we see that a .5 percent tax on exchange transaction wouldaugment government revenues globally by as much as $300 to $400 billion per anumand dev oting merely 10-20 percent of that revenue to a revolving fund forlong-term lending to Third World countries would be a healthy substitute forthe hot money on which some have become disastrously overdependent (McCallum,1995:16). The recognition and ceasing of financial instability and its globaltransmission is becoming more and more universally endorsed. To decide on aprudent and practical policy will prove to be a major hurdle of internationalfinancial leaders around the world. However, if we look closely, we will findthe locus of instability in financial markets to be deregulation and speculativeattacks. Government and central bankers can no longer adopt an attitude of benign neglect toward international financial instability as it becomesincreasingly apparent that there are far reaching consequences on real sectors. We can see that there is one policy that supersedes the rest. If the worldfinancial system hopes to curb these real sector ramifications of speculativeattacks and financial liberalization, then it becomes indisputable that the STTis an idea whose time has come. BIBLIOGRAPHYRichard N. Cooper, A Monetary System for the Future Foreign Affairs Fall,1984. Barry Eichengreen and Richard Portes, The Anatomy of Financial Crisis, inRichardPortes and Alexander Swoboda, Threats to International FinancialStability,(Cambridege University Press, 1987). Barry Eichengreen, James Tobin and Charles Wyplosz, Two Cases for Sand in theWhellsof International Finance Economic Journal, 1995. Jacob Frenkel, The International Monetary System: Should It Be Reformed inPhilipKing, editor, International Economics and International Economic Policy(McGraw-Hill,1990). Ilene Grabel, Crossing Borders: A Case for Cooperation in InternationalFinancialMarkets, in Gerald Epstein, Julie Graham, Jessica Nembard (eds.),Creating aNew World Economy: Forces of Change and Plans of Action (TempleUniversityPress, 1993). Charles Hakkio, Should we Throw Sand in the Gears of Financial Markets?FederalReserve Bank of Kansas City Economic Review, 1994. Richard Herring and Robert Litan, Financial Regulation in the Global Economy(Brookings Institution, 1995). Ethan Kapstein, Shockproof: The End of Financial Crisis Foreign Affairs,January/February 1996. Charles P. Kindleberger, The World in Depression (London: Penguin 1973). Paul Krugman, International Aspects of Financial Crises in Martin Feldstein,ed., TheRisk of Economic Crisis (Chicago: University of Chicago Press, 1991). John McCallum, Managers and Unstable Financial Markets Business QuarterlyJanuary1, 1995. James Tobin, A proposal for international monetary reform Eastern EconomicJournal1978, volume 4. John Williamson, The Failure of World Monetary Reform 1971-1974) (NY:NYU Press,1977)L.B. Yeager, International Monetary Relations: Theory, History, and Policy 1976. . Category: Business

Monday, April 20, 2020

Thin Layer Chromatography and Column Chromatography free essay sample

Introduction Chromatography is a technique used to separate a mixture into its individual components. In this experiment, chromatography is done by using a thin layer chromatography (TLC) plate and filter paper. The word ‘chromatography’ itself means the separation of colours. However, nowadays, both coloured and colourless compound are used in chromatography by various methods. In chromatography, the separation process of mixture is mainly based upon the polarity and molecular weight of sample. Then, the separation involves mobile phase and stationary phase. The mixture to be separated is applied to an immovable solid surface, which is the stationary phase, such as TLC plate and the filter paper. Then, suitable solvent is then added to ‘wash’ the porous solid by the flow of solvent, which is the mobile phase. The mobile phase can be liquid (in liquid chromatography) which is in this experiment, or gas (as in gas chromatography). The porous solid, which is the stationary phase, adsorbs different substances depending on the polarity of the substance adsorbed to it. We will write a custom essay sample on Thin Layer Chromatography and Column Chromatography or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page The term â€Å"adsorption† means the adhesion or stickyness of a substance to the surface of another substance. As mentioned, chromatography is based on polarity. So, a mixture of compound is separated or adsorbed differently on porous solid (stationary phase) based on the polarity of both the compound itself and also the stationary phase. By the concept of â€Å"like attracts like†, a polar stationary phase will adsorb a polar components more strongly than a non-polar component, which also indicates that a non-polar components will be removed along the solvent more easily and faster than the polar compounds. It is the same case as where a polar solvent is used. The polar component will be moved along the solvent more quickly and hence, leave behind the non-polar component which is move more slowly and removed later. The solvent (mobile phase) moves through the stationary phase (porous solid) by capillary action. The solvent ‘attracts’ or pulls the molecules of mixture, which is then separated at different rates. Molecular weight also affects the separation of mixture into its components. Components having higher molecular weight will be left behind. In contrast, component of lowest molecular weight will be the fastest to be removed. Part 1: TLC analysis of analgesic drugs Method 1. Prepare a TLC plate with measurement shown in figure. Diagram A developing chamber was developed in a 250 mL beaker, with a half-piece of filter paper inside, and aluminium foil to cover. The eluent is a 15 mL mixture of 2:1 mixture of ethyl acetate: hexane. 3. The eluent must not exceed depth of 1 cm in the beaker. 5 drops of acetic acid was added into the beaker and mix. The TLC plate was then placed in the beaker and ensured the solvent level is below the pencil mark. 4. After the solvent was risen to near the top of the plate, the plate was removed and the solvent front was marked with a pencil. The solvent was allowed to evaporate in the fume hood. 5. By using 5 different capillary tubes for 5 different samples, the sample was spot on the origin line. The sequence from the left (first spot) is acetaminophen solution, caffeine, unknown A, aspirin and unknown B. 6. The TLC plate was then placed in the iodine chamber for few minutes. 7. The plate was then observed under UV lamp. 8. The spot was outlined with a 2B pencil. 9. The plate was then sketched and the retention factor, Rf value is calculated. 10. The unknown drug based on the Rf value is determined. Apparatus